KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction

Silvana B. De Lorenzo; Alyssa M. Vrieze; Ruth A. Johnson; Karen R. Lien; Karl A. Nath; Vesna D. Garovic; Khashayarsha Khazaie; Joseph P. Grande

doi:10.1371/journal.pone.0266454

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Open Access

Peer-reviewed

Research Article

KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction

Silvana B. De Lorenzo,

Roles Conceptualization, Data curation, Formal analysis, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Alyssa M. Vrieze,

Roles Data curation

Affiliation Department of Comparative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Ruth A. Johnson,

Roles Data curation

Affiliation Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Karen R. Lien,

Roles Data curation

Affiliation Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Karl A. Nath,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliation Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Vesna D. Garovic,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliation Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Khashayarsha Khazaie,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Joseph P. Grande

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: grande.joseph@mayo.edu

Affiliation Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

https://orcid.org/0000-0001-5674-1682

⨯

KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction

Silvana B. De Lorenzo,
Alyssa M. Vrieze,
Ruth A. Johnson,
Karen R. Lien,
Karl A. Nath,
Vesna D. Garovic,
Khashayarsha Khazaie,
Joseph P. Grande

Published: April 12, 2022
https://doi.org/10.1371/journal.pone.0266454

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Gene expression
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