Signatures of selection and drivers for novel mutation on transmission-blocking vaccine candidate Pfs25 gene in western Kenya

• Kevin O. Ochwedo ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kevinochwedo@gmail.com (KOO); dzhong@hs.uci.edu (DZ)

  Affiliations Department of Biology, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya, Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya

  https://orcid.org/0000-0002-4510-8344

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• Shirley A. Onyango,

  Roles Methodology, Writing – review & editing

  Affiliations Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya, School of Zoological Sciences, Kenyatta University, Nairobi, Kenya

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• Collince J. Omondi,

  Roles Methodology

  Affiliations Department of Biology, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya, Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya

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• Pauline W. Orondo,

  Roles Methodology

  Affiliations Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya, Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya

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• Benyl M. Ondeto,

  Roles Methodology

  Affiliations Department of Biology, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya, Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya

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• Ming-Chieh Lee,

  Roles Methodology, Visualization

  Affiliation Program in Public Health, College of Health Sciences, University of California, Irvine, Irvine, California, United States of America

  https://orcid.org/0000-0002-2462-6089

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• Harrysone E. Atieli,

  Roles Project administration

  Affiliations Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya, School of Public Health and Community Development, Maseno University, Kisumu, Kenya

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• Sidney O. Ogolla,

  Roles Project administration, Writing – review & editing

  Affiliation Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya

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• Andrew K. Githeko,

  Roles Conceptualization, Writing – review & editing

  Affiliations Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya, Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya

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• Antony C. A. Otieno,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Biology, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya

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• Wolfgang R. Mukabana,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Biology, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya, Sub-Saharan Africa International Centre for Excellence in Malaria Research, Homa Bay, Kenya

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• Guiyun Yan,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Program in Public Health, College of Health Sciences, University of California, Irvine, Irvine, California, United States of America

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• Daibin Zhong ,

  Roles Conceptualization, Data curation, Methodology, Software, Validation, Writing – review & editing

  * E-mail: kevinochwedo@gmail.com (KOO); dzhong@hs.uci.edu (DZ)

  Affiliation Program in Public Health, College of Health Sciences, University of California, Irvine, Irvine, California, United States of America

  https://orcid.org/0000-0002-2771-9598

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• James W. Kazura

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliation Centre for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio, United States of America

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