Inflammatory responses in SARS-CoV-2 associated Multisystem Inflammatory Syndrome and Kawasaki Disease in children: An observational study

• G. Biesbroek ,

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: g.biesbroek@amsterdamumc.nl

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0002-5600-9587

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• B. Kapitein ,

  Contributed equally to this work with: B. Kapitein, I. M. Kuipers

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Pediatric Intensive Care Unit, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• I. M. Kuipers ,

  Contributed equally to this work with: B. Kapitein, I. M. Kuipers

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Pediatric Cardiology, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• M. P. Gruppen,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• D. van Stijn,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• T. E. Peros,

  Roles Data curation, Formal analysis, Project administration, Writing – review & editing

  Affiliation Pediatric Intensive Care Unit, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0002-6122-8127

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• M. van Veenendaal,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology and Infectious Disease, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

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• M. H. A. Jansen,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology and Infectious Disease, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

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• C. W. van der Zee,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatrics, Hilversum, The Netherlands

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• M. van der Kuip,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• E. G. J. von Asmuth,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatrics, Willem-Alexander Children’s Hospital, Leiden University Medical Center, Leiden, The Netherlands

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• M. G. Mooij,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatrics, Willem-Alexander Children’s Hospital, Leiden University Medical Center, Leiden, The Netherlands

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• M. E. J. den Boer,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatrics, Medical Spectrum Twente, Enschede, The Netherlands

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• G. W. Landman,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Internal medicine, Gelre Hospital, Apeldoorn, The Netherlands

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• M. A. van Houten,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatrics, Spaarne Hospital, Haarlem, The Netherlands

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• D. Schonenberg-Meinema,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0001-9416-6631

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• A. M. Tutu van Furth,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• M. Boele van Hensbroek,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• H. Scherpbier,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• K. E. van Meijgaarden,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

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• T. H. M. Ottenhoff,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

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• S. A. Joosten,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

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• N. Ketharanathan,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatric Surgery and Intensive Care, Erasmus Medical Center, Sophia Children’s Hospital, Rotterdam, The Netherlands

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• M. Blink,

  Roles Data curation, Writing – review & editing

  Affiliation Pediatric Intensive Care Unit, Willem-Alexander Children’s Hospital, Leiden University Medical Center, Leiden, The Netherlands

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• C. L. H. Brackel,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Pediatrics, Hilversum, The Netherlands, Department of Pediatric Pulmonology, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• H. L. Zaaijer,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Virology, Sanquin Research Institute, University of Amsterdam, Amsterdam, The Netherlands

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• P. Hombrink,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Blood Cell Research, Sanquin Research Institute, University of Amsterdam, Amsterdam, The Netherlands

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• J. M. van den Berg,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands

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• E. P. Buddingh ,

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ EPB and TWK also contributed equally to this work.

  Affiliation Department of Pediatrics, Willem-Alexander Children’s Hospital, Leiden University Medical Center, Leiden, The Netherlands

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•  [ ... ],
• T. W. Kuijpers

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ EPB and TWK also contributed equally to this work.

  Affiliations Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands, Department of Blood Cell Research, Sanquin Research Institute, University of Amsterdam, Amsterdam, The Netherlands

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