CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma

Yurie Yamamoto; Atsushi Sugimoto; Koji Maruo; Gen Tsujio; Tomohiro Sera; Shuhei Kushiyama; Sadaaki Nishimura; Kenji Kuroda; Shingo Togano; Shinpei Eguchi; Ryota Tanaka; Kenjiro Kimura; Ryosuke Amano; Masaichi Ohira; Masakazu Yashiro

doi:10.1371/journal.pone.0266027

Loading metrics

Open Access

Peer-reviewed

Research Article

CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma

Yurie Yamamoto,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Writing – original draft

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Atsushi Sugimoto,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Koji Maruo,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Gen Tsujio,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Tomohiro Sera,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Shuhei Kushiyama,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Sadaaki Nishimura,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Kenji Kuroda,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Shingo Togano,

Roles Resources

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Shinpei Eguchi,

Roles Resources

Affiliation Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Ryota Tanaka,

Roles Resources

Affiliation Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Kenjiro Kimura,

Roles Writing – review & editing

Affiliation Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Ryosuke Amano,

Roles Writing – review & editing

Affiliation Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Masaichi Ohira,

Roles Writing – review & editing

Affiliation Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
⨯
Masakazu Yashiro

Roles Writing – review & editing

* E-mail: m9312510@med.osaka-cu.ac.jp

Affiliations Molecular Oncology and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan, Cancer Center for Translational Research, Osaka City University Graduate School of Medicine, Osaka, Japan, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan

https://orcid.org/0000-0001-5743-7228

⨯

CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma

Yurie Yamamoto,
Atsushi Sugimoto,
Koji Maruo,
Gen Tsujio,
Tomohiro Sera,
Shuhei Kushiyama,
Sadaaki Nishimura,
Kenji Kuroda,
Shingo Togano,
Shinpei Eguchi

Published: April 4, 2022
https://doi.org/10.1371/journal.pone.0266027

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Gastric cancer
Is the Subject Area "Gastric cancer" applicable to this article?

Thanks for your feedback.
Metastasis
Is the Subject Area "Metastasis" applicable to this article?

Thanks for your feedback.
Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
Hepatocellular carcinoma
Is the Subject Area "Hepatocellular carcinoma" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Cholangiocarcinoma
Is the Subject Area "Cholangiocarcinoma" applicable to this article?

Thanks for your feedback.
MTT assay
Is the Subject Area "MTT assay" applicable to this article?

Thanks for your feedback.