Radotinib inhibits multiple myeloma cell proliferation via suppression of STAT3 signaling

Sook-Kyoung Heo; Eui-Kyu Noh; Hye Jin Seo; Yoo Jin Lee; SuJin Koh; Young Joo Min; Yunsuk Choi; Jae-Cheol Jo

doi:10.1371/journal.pone.0265958

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Open Access

Peer-reviewed

Research Article

Radotinib inhibits multiple myeloma cell proliferation via suppression of STAT3 signaling

Sook-Kyoung Heo,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
⨯
Eui-Kyu Noh,

Roles Data curation, Methodology, Project administration, Resources

Affiliation Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
⨯
Hye Jin Seo,

Roles Investigation, Methodology

Affiliation Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
⨯
Yoo Jin Lee,

Roles Resources, Software, Supervision

Affiliation Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
⨯
SuJin Koh,

Roles Supervision

Affiliation Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea

https://orcid.org/0000-0002-1545-8036

⨯
Young Joo Min,

Roles Supervision

Affiliation Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
⨯
Yunsuk Choi,

Roles Supervision, Validation

Affiliation Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
⨯
Jae-Cheol Jo

Roles Funding acquisition, Writing – review & editing

* E-mail: jcjo@uuh.ulsan.kr

Affiliations Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea, Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea

https://orcid.org/0000-0001-6014-7977

⨯

Radotinib inhibits multiple myeloma cell proliferation via suppression of STAT3 signaling

Sook-Kyoung Heo,
Eui-Kyu Noh,
Hye Jin Seo,
Yoo Jin Lee,
SuJin Koh,
Young Joo Min,
Yunsuk Choi,
Jae-Cheol Jo

Published: May 3, 2022
https://doi.org/10.1371/journal.pone.0265958

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