Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein

Prerna Arora; Anzhalika Sidarovich; Luise Graichen; Bojan Hörnich; Alexander Hahn; Markus Hoffmann; Stefan Pöhlmann

doi:10.1371/journal.pone.0265453

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Open Access

Peer-reviewed

Research Article

Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein

Prerna Arora,

Roles Investigation, Methodology, Writing – review & editing

Affiliations Infection Biology Unit, German Primate Center, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany
⨯
Anzhalika Sidarovich,

Roles Investigation, Methodology, Writing – review & editing

Affiliations Infection Biology Unit, German Primate Center, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany
⨯
Luise Graichen,

Roles Investigation

Affiliation Infection Biology Unit, German Primate Center, Göttingen, Germany
⨯
Bojan Hörnich,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Junior Research Group Herpesviruses - Infection Biology Unit, German Primate Center, Göttingen, Germany
⨯
Alexander Hahn,

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

Affiliation Junior Research Group Herpesviruses - Infection Biology Unit, German Primate Center, Göttingen, Germany

https://orcid.org/0000-0003-4171-2744

⨯
Markus Hoffmann ,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

* E-mail: mhoffmann@dpz.eu (MH); spoehlmann@dpz.eu (SP)

Affiliations Infection Biology Unit, German Primate Center, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

https://orcid.org/0000-0003-4603-7696

⨯
Stefan Pöhlmann

Roles Conceptualization, Funding acquisition, Supervision, Validation, Writing – original draft

* E-mail: mhoffmann@dpz.eu (MH); spoehlmann@dpz.eu (SP)

Affiliations Infection Biology Unit, German Primate Center, Göttingen, Germany, Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany

https://orcid.org/0000-0001-6086-9136

⨯

Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein

Prerna Arora,
Anzhalika Sidarovich,
Luise Graichen,
Bojan Hörnich,
Alexander Hahn,
Markus Hoffmann,
Stefan Pöhlmann

Published: March 25, 2022
https://doi.org/10.1371/journal.pone.0265453

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Cell fusion
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Plasmid construction
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Protein cleavage
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