Validation of an online application to identify potential immune-related adverse events associated with immune checkpoint inhibitors based on the patient’s symptoms

Takahiro Osawa; Takashige Abe; Hiroshi Kikuchi; Ryuji Matsumoto; Sachiyo Murai; Takafumi Nakao; Shinji Tanaka; Ayu Watanabe; Nobuo Shinohara

doi:10.1371/journal.pone.0265230

Loading metrics

Open Access

Peer-reviewed

Research Article

Validation of an online application to identify potential immune-related adverse events associated with immune checkpoint inhibitors based on the patient’s symptoms

Takahiro Osawa ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft

* E-mail: taka0573@gmail.com

Affiliation Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

https://orcid.org/0000-0003-4444-7958

⨯
Takashige Abe,

Roles Supervision, Writing – review & editing

Affiliation Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Hiroshi Kikuchi,

Roles Supervision, Writing – review & editing

Affiliation Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Ryuji Matsumoto,

Roles Supervision, Writing – review & editing

Affiliation Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Sachiyo Murai,

Roles Supervision, Writing – review & editing

Affiliation Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Takafumi Nakao,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Pharmacovigilance Division, Ono Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Shinji Tanaka,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Pharmacovigilance Division, Ono Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Ayu Watanabe,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Pharmacovigilance Division, Ono Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Nobuo Shinohara

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

Affiliation Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯

Validation of an online application to identify potential immune-related adverse events associated with immune checkpoint inhibitors based on the patient’s symptoms

Takahiro Osawa,
Takashige Abe,
Hiroshi Kikuchi,
Ryuji Matsumoto,
Sachiyo Murai,
Takafumi Nakao,
Shinji Tanaka,
Ayu Watanabe,
Nobuo Shinohara

Published: March 15, 2022
https://doi.org/10.1371/journal.pone.0265230

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Adverse events
Is the Subject Area "Adverse events" applicable to this article?

Thanks for your feedback.
Pituitary gland
Is the Subject Area "Pituitary gland" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Renal cancer
Is the Subject Area "Renal cancer" applicable to this article?

Thanks for your feedback.
Thyroid
Is the Subject Area "Thyroid" applicable to this article?

Thanks for your feedback.
Cancer detection and diagnosis
Is the Subject Area "Cancer detection and diagnosis" applicable to this article?

Thanks for your feedback.
Database searching
Is the Subject Area "Database searching" applicable to this article?

Thanks for your feedback.