Antibiotics cause metabolic changes in mice primarily through microbiome modulation rather than behavioral changes

• Kale S. Bongers,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America

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• Roderick A. McDonald,

  Roles Investigation, Writing – review & editing

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America

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• Katherine M. Winner,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America, Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Nicole R. Falkowski,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America

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• Christopher A. Brown,

  Roles Formal analysis, Writing – review & editing

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America, Institute for Research on Innovation and Science, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America

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• Jennifer M. Baker,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America, Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Kevin J. Hinkle,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America

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• Daniel J. Fergle,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America

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• Robert P. Dickson

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – review & editing

  * E-mail: rodickso@med.umich.edu

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America, Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Weil Institute for Critical Care Research and Innovation, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-6875-4277

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