Four in one—Combination therapy using live Lactococcus lactis expressing three therapeutic proteins for the treatment of chronic non-healing wounds

• Jere Kurkipuro ,

  Contributed equally to this work with: Jere Kurkipuro, Igor Mierau

  Roles Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jere@aurealistherapeutics.com

  Affiliation Aurealis Therapeutics, Kuopio, Finland

  https://orcid.org/0000-0002-5239-6532

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• Igor Mierau ,

  Contributed equally to this work with: Jere Kurkipuro, Igor Mierau

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Aurealis Therapeutics, Kuopio, Finland

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• Thomas Wirth ,

  Roles Conceptualization, Investigation, Resources, Supervision

  ¶‡ TW, HS, and JY also contributed equally to this work.

  Affiliation Aurealis Therapeutics, Kuopio, Finland

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• Haritha Samaranayake ,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  ¶‡ TW, HS, and JY also contributed equally to this work.

  Affiliation Aurealis Therapeutics, Kuopio, Finland

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• Wesley Smith,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Aurealis Therapeutics, Kuopio, Finland

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• Hanna-Riikka Kärkkäinen,

  Roles Conceptualization, Writing – review & editing

  Affiliation Aurealis Therapeutics, Kuopio, Finland

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• Mirka Tikkanen,

  Roles Writing – review & editing

  Affiliation Aurealis Therapeutics, Kuopio, Finland

  ⨯
• Juha Yrjänheikki

  Roles Conceptualization, Project administration, Resources, Writing – review & editing

  ¶‡ TW, HS, and JY also contributed equally to this work.

  Affiliation Aurealis Therapeutics, Kuopio, Finland

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