Preliminary application of native Nephila edulis spider silk and fibrin implant causes granulomatous foreign body reaction in vivo in rat’s spinal cord

• Felix Koop ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  * E-mail: Koop.felix@mh-hannover.de

  Affiliation Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany

  https://orcid.org/0000-0001-7378-7877

  ⨯
• Sarah Strauß,

  Roles Conceptualization, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany

  ⨯
• Claas-Tido Peck,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany

  ⨯
• Thomas Aper,

  Roles Resources, Writing – review & editing

  Affiliation Cardiac, Thoracic, and Vascular Surgery, Hannover Medical School, Hannover, Germany

  ⨯
• Mathias Wilhelmi,

  Roles Resources, Writing – review & editing

  Affiliation Cardiac, Thoracic, and Vascular Surgery, Hannover Medical School, Hannover, Germany

  ⨯
• Christian Hartmann,

  Roles Formal analysis, Investigation, Resources, Visualization, Writing – review & editing

  Affiliation Department of Neuropathology, Hannover Medical School, Hannover, Germany

  ⨯
• Jan Hegermann,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliation Research Core Unit Electron Microscopy and Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany

  ⨯
• Julia Schipke,

  Roles Resources, Visualization, Writing – review & editing

  Affiliation Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany

  ⨯
• Peter M. Vogt,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany

  ⨯
• Vesna Bucan

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany

  ⨯