Suicide gene therapy by canine mesenchymal stem cell transduced with thymidine kinase in a u-87 glioblastoma murine model: Secretory profile and antitumor activity

• Antonio J. Villatoro ,

  Contributed equally to this work with: Antonio J. Villatoro, Cristina Alcoholado

  Roles Investigation, Writing – original draft

  * E-mail: antoniojvillatoro@gmail.com

  Affiliation Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain

  https://orcid.org/0000-0003-3407-0616

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• Cristina Alcoholado ,

  Contributed equally to this work with: Antonio J. Villatoro, Cristina Alcoholado

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain, Networking Research Center on Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), Madrid, Spain

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• María del Carmen Martín-Astorga,

  Roles Methodology, Writing – review & editing

  Affiliation Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain

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• Nuria Rubio,

  Roles Writing – review & editing

  Affiliation Cell Therapy Group, Catalonian Institute for Advanced Chemistry (IQAC-CSIC), Barcelona, Spain

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• Jerónimo Blanco,

  Roles Writing – review & editing

  Affiliation Cell Therapy Group, Catalonian Institute for Advanced Chemistry (IQAC-CSIC), Barcelona, Spain

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• Cristina Pilar Garrido,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain, Networking Research Center on Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), Madrid, Spain, Cell Therapy Group, Catalonian Institute for Advanced Chemistry (IQAC-CSIC), Barcelona, Spain

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• José Becerra

  Roles Investigation, Writing – review & editing

  Affiliations Laboratory of Bioengineering and Tissue Regeneration (LABRET), Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Málaga, IBIMA, Málaga, Spain, Networking Research Center on Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), Madrid, Spain, Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain

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