Hour-1 bundle adherence was associated with reduction of in-hospital mortality among patients with sepsis in Japan

• Yutaka Umemura,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliations Division of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka, Japan, Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

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• Toshikazu Abe ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: abetoshi111@gmail.com

  Affiliations Department of Emergency and Critical Care Medicine, Tsukuba Memorial Hospital, Tsukuba, Japan, Health Services Research and Development Center, University of Tsukuba, Tsukuba, Japan, Department of Health Services Research, Faculty of Medicine, University of Tsukuba, Japan

  https://orcid.org/0000-0002-8343-5151

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• Hiroshi Ogura,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

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• Seitato Fujishima,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Center for General Medicine Education, Keio University School of Medicine, Tokyo, Japan

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• Shigeki Kushimoto,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

  https://orcid.org/0000-0001-9232-5782

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• Atsushi Shiraishi,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Emergency and Trauma Center, Kameda Medical Center, Chiba, Japan

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• Daizoh Saitoh,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Traumatology, Research Institute, National Defense Medical College, Tokorozawa, Japan

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• Toshihiko Mayumi,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

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• Yasuhiro Otomo,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Trauma and Acute Critical Care Center, Medical Hospital, Tokyo Medical and Dental University, Tokyo, Japan

  https://orcid.org/0000-0002-9674-1369

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• Toru Hifumi,

  Roles Data curation, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Emergency and Critical Care Medicine, St. Luke’s International Hospital, Tokyo, Japan

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• Akiyoshi Hagiwara,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan

  https://orcid.org/0000-0003-0012-5180

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• Kiyotsugu Takuma,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Emergency & Critical Care Center, Kawasaki Municipal Kawasaki Hospital, Kawasaki, Japan

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• Kazuma Yamakawa,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Emergency Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan

  ⨯
• Yasukazu Shiino,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Acute Medicine, Kawasaki Medical School, Okayama, Japan

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• Taka-aki Nakada,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba, Japan

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• Takehiko Tarui,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Department of Emergency Medical Care, Kyorin University Faculty of Health Sciences, Tokyo, Japan

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• Kohji Okamoto,

  Roles Conceptualization, Methodology, Validation, Writing – review & editing

  Affiliation Department of Surgery, Center for Gastroenterology and Liver Disease, Kitakyushu City Yahata Hospital, Kitakyushu, Japan

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• Joji Kotani,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Disaster and Emergency Medicine, Department of Surgery Related, Kobe University Graduate School of Medicine, Kobe, Japan

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• Yuichiro Sakamoto,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Emergency and Critical Care Medicine, Saga University Hospital, Saga, Japan

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• Junichi Sasaki,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan

  https://orcid.org/0000-0002-5190-8524

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• Shin-ichiro Shiraishi,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Emergency and Critical Care Medicine, Aizu Chuo Hospital, Fukushima, Japan

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• Ryosuke Tsuruta,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Advanced Medical Emergency & Critical Care Center, Yamaguchi University Hospital, Yamaguchi, Japan

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• Tomohiko Masuno,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan

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• Naoshi Takeyama,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Advanced Critical Care Center, Aichi Medical University Hospital, Aichi, Japan

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• Norio Yamashita,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Advanced Emergency Medical Service Center Kurume University Hospital, Kurume, Japan

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• Hiroto Ikeda,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, Teikyo University School of Medicine, Tokyo, Japan

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• Masashi Ueyama,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Trauma, Critical Care Medicine, and Burn Center, Japan Community Healthcare Organization, Chukyo Hospital, Nagoya, Japan, Community Healthcare Organization, Chukyo Hospital, Nagoya, Japan

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•  [ ... ],
• Satoshi Gando

  Roles Conceptualization, Investigation, Methodology, Project administration, Validation, Writing – review & editing

  Affiliations Department of Anesthesiology and Critical Medicine, Hokkaido University Faculty of Medicine, Sapporo, Japan, Department of Acute and Critical Care Medicine, Sapporo Tokushukai Hospital, Sapporo, Japan

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