Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

Tsvetana Petrova; Kyle Bennett; Sambit Nanda; Sam Strickson; Cheryl L. Scudamore; Alan R. Prescott; Philip Cohen

doi:10.1371/journal.pone.0263151

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Open Access

Peer-reviewed

Research Article

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

Tsvetana Petrova ,

Contributed equally to this work with: Tsvetana Petrova, Kyle Bennett

Roles Data curation, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom

https://orcid.org/0000-0003-2425-2459

⨯
Kyle Bennett ,

Contributed equally to this work with: Tsvetana Petrova, Kyle Bennett

Roles Data curation, Funding acquisition, Investigation, Visualization

Affiliations MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom, Division of Cell Signalling, School of Life Sciences, University of Dundee, Dundee, United Kingdom
⨯
Sambit Nanda,

Roles Conceptualization, Data curation, Investigation, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom
⨯
Sam Strickson,

Roles Conceptualization, Investigation, Visualization

Affiliation MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom

https://orcid.org/0000-0002-9208-2028

⨯
Cheryl L. Scudamore,

Roles Data curation, Visualization

Affiliation Exepathology, Exeter, Devon, United Kingdom
⨯
Alan R. Prescott,

Roles Formal analysis, Visualization

Affiliation Dundee Imaging Facility and Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom

https://orcid.org/0000-0002-0747-7317

⨯
Philip Cohen

Roles Conceptualization, Data curation, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: p.cohen@dundee.ac.uk

Affiliation MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom
⨯

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

Tsvetana Petrova,
Kyle Bennett,
Sambit Nanda,
Sam Strickson,
Cheryl L. Scudamore,
Alan R. Prescott,
Philip Cohen

Published: February 14, 2022
https://doi.org/10.1371/journal.pone.0263151

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