Reversible domain closure modulates GlnBP ligand binding affinity

Qun Chen; Fang Li; Xiaobing Zuo; Jin Chen; Peiwu Qin; Chuhui Wang; Jin Xu; Danyu Yang; Baogang Xing; Ying Liu; Peng Jia; Linling Li; Chengming Yang; Dongmei Yu

doi:10.1371/journal.pone.0263102

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Open Access

Peer-reviewed

Research Article

Reversible domain closure modulates GlnBP ligand binding affinity

Qun Chen ,

Contributed equally to this work with: Qun Chen, Fang Li

Roles Formal analysis

Affiliation Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, Guangdong Province, China
⨯
Fang Li ,

Contributed equally to this work with: Qun Chen, Fang Li

Roles Writing – original draft, Writing – review & editing

Affiliation Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, Guangdong Province, China
⨯
Xiaobing Zuo,

Roles Data curation

Affiliation X-ray Science Division, Argonne National Laboratory, Argonne, IL, United States of America
⨯
Jin Chen,

Roles Supervision

Affiliation Institute of Chinese medical sciences, University of Macau, Macau, China
⨯
Peiwu Qin,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, Guangdong Province, China
⨯
Chuhui Wang,

Roles Writing – original draft

Affiliation Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, Guangdong Province, China
⨯
Jin Xu,

Roles Writing – review & editing

Affiliation Shenzhen Aier Eye Hospital, Futian District, Guangdong Province, China
⨯
Danyu Yang,

Roles Writing – original draft

Affiliation Shenzhen Aier Eye Hospital, Futian District, Guangdong Province, China
⨯
Baogang Xing,

Roles Writing – review & editing

Affiliation University of Science and Technology Hospital, Shenzhen, Guangdong Province, China
⨯
Ying Liu,

Roles Writing – review & editing

Affiliation Food Inspection & Quarantine Center, Shenzhen Custom, Shenzhen, Guangdong, China
⨯
Peng Jia,

Roles Conceptualization

Affiliation Food Inspection & Quarantine Center, Shenzhen Custom, Shenzhen, Guangdong, China
⨯
Linling Li,

Roles Writing – review & editing

Affiliation Shenzhen Maternity and Child Healthcare Hospital, Affiliated to Southern Medical University, Shenzhen, Guangdong, China
⨯
Chengming Yang ,

Roles Investigation

* E-mail: yudongmei@sdu.edu.cn (DY); hanks281128@163.com (CY)

Affiliation University of Science and Technology Hospital, Shenzhen, Guangdong Province, China
⨯
Dongmei Yu

Roles Supervision, Writing – review & editing

* E-mail: yudongmei@sdu.edu.cn (DY); hanks281128@163.com (CY)

Affiliation School of Mechanical, Electrical & Information Engineering, Shandong University, Weihai, Shandong Province, China

https://orcid.org/0000-0002-2436-4744

⨯

Reversible domain closure modulates GlnBP ligand binding affinity

Qun Chen,
Fang Li,
Xiaobing Zuo,
Jin Chen,
Peiwu Qin,
Chuhui Wang,
Jin Xu,
Danyu Yang,
Baogang Xing,
Ying Liu

Published: April 21, 2022
https://doi.org/10.1371/journal.pone.0263102

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