Repeated glucose spikes and insulin resistance synergistically deteriorate endothelial function and bardoxolone methyl ameliorates endothelial dysfunction

• Kazuma Ogiso,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan

  https://orcid.org/0000-0002-9626-0127

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• Sigfrid Casmir Shayo,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan

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• Shigeru Kawade,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan

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• Hiroshi Hashiguchi,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan

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• Takahisa Deguchi,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan

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• Yoshihiko Nishio

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: ynishio@m3.kufm.kagoshima-u.ac.jp

  Affiliation Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan

  https://orcid.org/0000-0001-7677-318X

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