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Open Access
Peer-reviewed
Research Article
Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration
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Shreyasi Chatterjee ,
Contributed equally to this work with: Shreyasi Chatterjee, Megan Sealey
Roles Formal analysis, Investigation, Methodology, Project administration, Writing – original draft
Affiliations School of Biological Sciences, University of Southampton, Southampton, United Kingdom, Department of Biochemistry, School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom
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Megan Sealey ,
Contributed equally to this work with: Shreyasi Chatterjee, Megan Sealey
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Eva Ruiz,
Roles Investigation, Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Chrysia M. Pegasiou,
Roles Resources
Affiliations School of Biological Sciences, University of Southampton, Southampton, United Kingdom, School of Life Sciences, University of Sussex, Brighton, United Kingdom
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Keeley Brookes,
Roles Methodology
Affiliation Department of Biochemistry, School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom
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Sam Green,
Roles Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Anna Crisford,
Roles Investigation, Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Michael Duque-Vasquez,
Roles Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Emma Luckett,
Roles Investigation, Methodology
Affiliations School of Biological Sciences, University of Southampton, Southampton, United Kingdom, Department of Neuroscience, KU Leuven, Leuven, Belgium
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Rebecca Robertson,
Roles Investigation, Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Philippa Richardson,
Roles Investigation, Methodology
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Girish Vajramani,
Roles Methodology, Resources
Affiliation Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton, Southampton, United Kingdom
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Paul Grundy,
Roles Investigation, Methodology
Affiliation Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton, Southampton, United Kingdom
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Diederik Bulters,
Roles Investigation, Methodology
Affiliations Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton, Southampton, United Kingdom, Faculty of Medicine, Clinical Neurosciences, Clinical and Experimental Sciences, University of Southampton, Southampton, United Kingdom
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Christopher Proud,
Roles Writing – review & editing
Affiliations School of Biological Sciences, University of Southampton, Southampton, United Kingdom, Lifelong Health, South Australian Health and Medical Research Institute, SAHMRI, and School of Biological Sciences, University of Adelaide, Adelaide, Australia
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Mariana Vargas-Caballero ,
Roles Investigation, Methodology, Resources, Writing – review & editing
* E-mail: A.Mudher@soton.ac.uk (AM); M.Vargas-Caballero@soton.ac.uk (MV-C)
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Amritpal Mudher
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
* E-mail: A.Mudher@soton.ac.uk (AM); M.Vargas-Caballero@soton.ac.uk (MV-C)
Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
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Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration
- Shreyasi Chatterjee,
- Megan Sealey,
- Eva Ruiz,
- Chrysia M. Pegasiou,
- Keeley Brookes,
- Sam Green,
- Anna Crisford,
- Michael Duque-Vasquez,
- Emma Luckett,
- Rebecca Robertson
- Published: January 26, 2023
- https://doi.org/10.1371/journal.pone.0262792