Multi attribute method implementation using a High Resolution Mass Spectrometry platform: From sample preparation to batch analysis

Sofia B. Carvalho; Ricardo A. Gomes; Anja Pfenninger; Martina Fischer; Michaela Strotbek; Inês A. Isidro; Nihal Tugçu; Patrícia Gomes-Alves

doi:10.1371/journal.pone.0262711

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Open Access

Peer-reviewed

Research Article

Multi attribute method implementation using a High Resolution Mass Spectrometry platform: From sample preparation to batch analysis

Sofia B. Carvalho,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliations iBET, Instituto de Biologia Experimental e Tecnologica, Oeiras, Portugal, ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal
⨯
Ricardo A. Gomes,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliations iBET, Instituto de Biologia Experimental e Tecnologica, Oeiras, Portugal, ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal
⨯
Anja Pfenninger,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Sanofi R&D, Biologics Development, Industriepark Höchst, Frankfurt am Main, Germany
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Martina Fischer,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Sanofi R&D, Biologics Development, Industriepark Höchst, Frankfurt am Main, Germany
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Michaela Strotbek,

Roles Funding acquisition, Project administration

Affiliation Sanofi R&D, Biologics Development, Industriepark Höchst, Frankfurt am Main, Germany
⨯
Inês A. Isidro,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliations iBET, Instituto de Biologia Experimental e Tecnologica, Oeiras, Portugal, ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal
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Nihal Tugçu,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Mammalian Platform, Global CMC Development, Sanofi, Framingham, MA, United States of America
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Patrícia Gomes-Alves

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: palves@ibet.pt

Affiliations iBET, Instituto de Biologia Experimental e Tecnologica, Oeiras, Portugal, ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal

https://orcid.org/0000-0001-7245-6785

⨯

Multi attribute method implementation using a High Resolution Mass Spectrometry platform: From sample preparation to batch analysis

Sofia B. Carvalho,
Ricardo A. Gomes,
Anja Pfenninger,
Martina Fischer,
Michaela Strotbek,
Inês A. Isidro,
Nihal Tugçu,
Patrícia Gomes-Alves

Published: January 27, 2022
https://doi.org/10.1371/journal.pone.0262711

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