Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

Annalisa Trecarichi; Natalie A. Duggett; Lucy Granat; Samantha Lo; Afshan N. Malik; Lorena Zuliani-Álvarez; Sarah J. L. Flatters

doi:10.1371/journal.pone.0262544

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Open Access

Peer-reviewed

Research Article

Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

Annalisa Trecarichi ,

Contributed equally to this work with: Annalisa Trecarichi, Natalie A. Duggett

Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
⨯
Natalie A. Duggett ,

Contributed equally to this work with: Annalisa Trecarichi, Natalie A. Duggett

Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
⨯
Lucy Granat,

Roles Investigation

Affiliation Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
⨯
Samantha Lo,

Roles Investigation

Affiliation Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
⨯
Afshan N. Malik,

Roles Conceptualization, Methodology, Resources, Writing – original draft, Writing – review & editing

Affiliation Department of Diabetes, School of Life Course Sciences, King’s College London, London, United Kingdom
⨯
Lorena Zuliani-Álvarez,

Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
⨯
Sarah J. L. Flatters

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sarah.flatters@kcl.ac.uk

Affiliation Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom

https://orcid.org/0000-0001-7129-3670

⨯

Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

Annalisa Trecarichi,
Natalie A. Duggett,
Lucy Granat,
Samantha Lo,
Afshan N. Malik,
Lorena Zuliani-Álvarez,
Sarah J. L. Flatters

Published: January 11, 2022
https://doi.org/10.1371/journal.pone.0262544

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