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Open Access

Peer-reviewed

Research Article

Cryptotanshinone inhibits proliferation and induces apoptosis of breast cancer MCF-7 cells via GPER mediated PI3K/AKT signaling pathway

Danning Shi,

Roles Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China
⨯
Hongbo Li,

Roles Data curation, Formal analysis, Software

Affiliation Department of Gynecology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, 712000, China
⨯
Zeye Zhang,

Roles Methodology, Software, Writing – review & editing

Affiliation School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China
⨯
Yueshuang He,

Roles Data curation, Formal analysis, Methodology

Affiliation School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China
⨯
Meng Chen,

Roles Writing – review & editing

Affiliation School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China
⨯
Liping Sun,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China
⨯
Piwen Zhao

Roles Funding acquisition, Project administration, Writing – review & editing

* E-mail: pw__zhao@163.com

Affiliation School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China

https://orcid.org/0000-0001-6993-1135

⨯

Cryptotanshinone inhibits proliferation and induces apoptosis of breast cancer MCF-7 cells via GPER mediated PI3K/AKT signaling pathway

Danning Shi,
Hongbo Li,
Zeye Zhang,
Yueshuang He,
Meng Chen,
Liping Sun,
Piwen Zhao

x

Published: January 21, 2022
https://doi.org/10.1371/journal.pone.0262389

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Cyclins
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Apoptosis
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Breast cancer
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Estradiol
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Cell cycle and cell division
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Cancers and neoplasms
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Estrogens
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Small interfering RNA
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