Identification of an early-stage Parkinson’s disease neuromarker using event-related potentials, brain network analytics and machine-learning

• Sharon Hassin-Baer ,

  Contributed equally to this work with: Sharon Hassin-Baer, Oren S. Cohen

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: shassin@tauex.tau.ac.il

  Affiliations Movement Disorders Institute and Department of Neurology, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

  https://orcid.org/0000-0001-7657-0171

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• Oren S. Cohen ,

  Contributed equally to this work with: Sharon Hassin-Baer, Oren S. Cohen

  Roles Conceptualization, Data curation, Methodology, Project administration

  Affiliations Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Israel

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• Simon Israeli-Korn,

  Roles Data curation, Writing – review & editing

  Affiliations Movement Disorders Institute and Department of Neurology, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

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• Gilad Yahalom,

  Roles Data curation

  Affiliation Department of Neurology and Movement Disorders Clinic, Shaare Zedek Medical Center, Jerusalem, Israel

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• Sandra Benizri,

  Roles Data curation

  Affiliation Movement Disorders Unit, Functional Neurosurgery Center, Assuta Ramat Ha Hayal Hospital, Tel Aviv, Israel

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• Daniel Sand,

  Roles Project administration, Visualization, Writing – review & editing

  Affiliations elminda Ltd., Herzliya, Israel, Faculty of Medicine, Department of Medical Neurobiology, The Hebrew University of Jerusalem, Ein Kerem, Jerusalem, Israel

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• Gil Issachar,

  Roles Methodology, Software, Writing – review & editing

  Affiliation elminda Ltd., Herzliya, Israel

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• Amir B. Geva,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Software

  Affiliations elminda Ltd., Herzliya, Israel, Department of Electrical and Computer Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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• Revital Shani-Hershkovich ,

  Roles Formal analysis, Project administration, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work

  Affiliation elminda Ltd., Herzliya, Israel

  https://orcid.org/0000-0001-5786-0077

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• Ziv Peremen

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work

  Affiliation elminda Ltd., Herzliya, Israel

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