A rare CTSC mutation in Papillon-Lefèvre Syndrome results in abolished serine protease activity and reduced NET formation but otherwise normal neutrophil function

• Felix P. Sanchez Klose ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  * E-mail: Felix.Klose@gu.se

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

  https://orcid.org/0000-0003-0166-5875

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• Halla Björnsdottir,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Agnes Dahlstrand Rudin,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Tishana Persson,

  Roles Data curation, Investigation

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Arsham Khamzeh,

  Roles Data curation, Investigation

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Martina Sundqvist,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Sara Thorbert-Mros,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Specialist Clinic of Periodontics, Gothenburg, Public Dental Service, Region Västra Götaland, Sweden

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• Régis Dieckmann,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Karin Christenson,

  Roles Data curation, Investigation, Methodology, Supervision, Writing – original draft

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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• Johan Bylund

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

  https://orcid.org/0000-0002-9094-6478

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