Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells

Shruti Mohan; Ryan Lafferty; Neil Tanday; Peter R. Flatt; R. Charlotte Moffett; Nigel Irwin

doi:10.1371/journal.pone.0261608

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Peer-reviewed

Research Article

Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells

Shruti Mohan,

Roles Data curation, Formal analysis, Investigation, Validation, Writing – original draft

Affiliation SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, United Kingdom
⨯
Ryan Lafferty,

Roles Data curation, Investigation, Methodology, Validation, Writing – original draft

Affiliation SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, United Kingdom
⨯
Neil Tanday,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliation SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, United Kingdom
⨯
Peter R. Flatt,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft

Affiliation SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, United Kingdom
⨯
R. Charlotte Moffett,

Roles Funding acquisition, Project administration, Supervision, Visualization

Affiliation SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, United Kingdom
⨯
Nigel Irwin

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft

* E-mail: n.irwin@ulster.ac.uk

Affiliation SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, United Kingdom

https://orcid.org/0000-0003-4855-964X

⨯

Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells

Shruti Mohan,
Ryan Lafferty,
Neil Tanday,
Peter R. Flatt,
R. Charlotte Moffett,
Nigel Irwin

Published: December 20, 2021
https://doi.org/10.1371/journal.pone.0261608

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