(More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy

Samuel A. Hendley; Aarushi Bhargava; Christy K. Holland; Geoffrey D. Wool; Osman Ahmed; Jonathan D. Paul; Kenneth B. Bader

doi:10.1371/journal.pone.0261567

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Peer-reviewed

Research Article

(More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy

Samuel A. Hendley,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliation Committee on Medical Physics, University of Chicago, Chicago, Illinois, United States of America
⨯
Aarushi Bhargava,

Roles Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

Affiliation Department of Radiology, University of Chicago, Chicago, Illinois, United States of America
⨯
Christy K. Holland,

Roles Conceptualization, Writing – review & editing

Affiliations Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, United States of America
⨯
Geoffrey D. Wool,

Roles Formal analysis, Validation, Visualization, Writing – review & editing

Affiliation Department of Pathology, University of Chicago, Chicago, Illinois, United States of America
⨯
Osman Ahmed,

Roles Data curation, Methodology, Resources, Writing – review & editing

Affiliation Department of Radiology, University of Chicago, Chicago, Illinois, United States of America
⨯
Jonathan D. Paul,

Roles Conceptualization, Data curation, Methodology, Resources, Writing – review & editing

Affiliation Department of Medicine, University of Chicago, Chicago, Illinois, United States of America
⨯
Kenneth B. Bader

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: baderk@uchicago.edu

Affiliations Committee on Medical Physics, University of Chicago, Chicago, Illinois, United States of America, Department of Radiology, University of Chicago, Chicago, Illinois, United States of America

https://orcid.org/0000-0003-2384-3150

⨯

(More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy

Samuel A. Hendley,
Aarushi Bhargava,
Christy K. Holland,
Geoffrey D. Wool,
Osman Ahmed,
Jonathan D. Paul,
Kenneth B. Bader

Published: January 4, 2022
https://doi.org/10.1371/journal.pone.0261567

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Catheters
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