Implications of OPRM1 and CYP2B6 variants on treatment outcomes in methadone-maintained patients in Ontario: Exploring sex differences

• Caroul Chawar,

  Roles Conceptualization, Formal analysis, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliations Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada, Department of Psychiatry and Behavioural Neurosciences, St. Joseph’s Healthcare Hamilton, Hamilton, ON, Canada

  https://orcid.org/0000-0001-8935-5454

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• Alannah Hillmer,

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliations Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada, Department of Psychiatry and Behavioural Neurosciences, St. Joseph’s Healthcare Hamilton, Hamilton, ON, Canada

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• Amel Lamri,

  Roles Methodology, Software, Writing – review & editing

  Affiliations Department of Medicine, McMaster University, Hamilton, ON, Canada, Population Health Research Institute, Hamilton, ON, Canada

  https://orcid.org/0000-0001-7182-0661

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• Flavio Kapczinski,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Psychiatry and Behavioural Neurosciences, St. Joseph’s Healthcare Hamilton, Hamilton, ON, Canada

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• Lehana Thabane,

  Roles Methodology, Writing – review & editing

  Affiliations Population Health Research Institute, Hamilton, ON, Canada, Department of Health Research Method, Evidence, and Impact, McMaster University, Hamilton, ON, Canada, Father Sean O’Sullivan Research Centre, St. Joseph’s Healthcare Hamilton, Hamilton, ON, Canada

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• Guillaume Pare,

  Roles Methodology, Writing – review & editing

  Affiliations Population Health Research Institute, Hamilton, ON, Canada, Department of Health Research Method, Evidence, and Impact, McMaster University, Hamilton, ON, Canada

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• Zainab Samaan

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  * E-mail: samaanz@mcmaster.ca

  Affiliation Department of Psychiatry and Behavioural Neurosciences, St. Joseph’s Healthcare Hamilton, Hamilton, ON, Canada

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