Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy

Julyanne Brassard; Meredith Elizabeth Gill; Emilie Bernatchez; Véronique Desjardins; Joanny Roy; Philippe Joubert; David Marsolais; Marie-Renée Blanchet

doi:10.1371/journal.pone.0260636

Loading metrics

Open Access

Peer-reviewed

Research Article

Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy

Julyanne Brassard,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
Meredith Elizabeth Gill,

Roles Investigation

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
Emilie Bernatchez,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
Véronique Desjardins,

Roles Investigation

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
Joanny Roy,

Roles Investigation

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
Philippe Joubert,

Roles Conceptualization, Writing – review & editing

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
David Marsolais,

Roles Conceptualization, Writing – review & editing

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada
⨯
Marie-Renée Blanchet

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

* E-mail: Marie-Renee.Blanchet@criucpq.ulaval.ca

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada

https://orcid.org/0000-0002-2711-1937

⨯

Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy

Julyanne Brassard,
Meredith Elizabeth Gill,
Emilie Bernatchez,
Véronique Desjardins,
Joanny Roy,
Philippe Joubert,
David Marsolais,
Marie-Renée Blanchet

Published: November 30, 2021
https://doi.org/10.1371/journal.pone.0260636

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Secondary lung tumors
Is the Subject Area "Secondary lung tumors" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Major histocompatibility complex
Is the Subject Area "Major histocompatibility complex" applicable to this article?

Thanks for your feedback.