Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques

Gabriella Bergamini; Maria Elisa Perico; Stefano Di Palma; Daniela Sabatini; Filippo Andreetta; Rossella Defazio; Antonio Felici; Livia Ferrari

doi:10.1371/journal.pone.0260627

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Open Access

Peer-reviewed

Research Article

Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques

Gabriella Bergamini ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: gabriella.bergamini@evotec.com

Affiliation Translational Microbiology, Antibacterial Discovery, Aptuit (Verona) S.r.l., an Evotec Company DD&D Research Centre, Verona, Italy

https://orcid.org/0000-0002-3426-9935

⨯
Maria Elisa Perico,

Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

Affiliation In vitro Pharmacology, Aptuit (Verona) S.r.l., an Evotec Company DD&D Research Centre, Verona, Italy
⨯
Stefano Di Palma,

Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

Affiliation Pathology, Preclinical Development, Aptuit (Verona) S.r.l., an Evotec Company, DD&D Research Centre, Verona, Italy

https://orcid.org/0000-0002-9466-3918

⨯
Daniela Sabatini,

Roles Data curation, Formal analysis, Investigation, Validation, Visualization

Affiliation In vitro Pharmacology, Microbiology Discovery, Aptuit (Verona) S.r.l., an Evotec Company, DD&D Research Centre, Verona, Italy
⨯
Filippo Andreetta,

Roles Data curation, Formal analysis, Validation

Affiliation In vitro Pharmacology, Aptuit (Verona) S.r.l., an Evotec Company DD&D Research Centre, Verona, Italy
⨯
Rossella Defazio,

Roles Data curation, Formal analysis, Validation

Affiliation Pathology, Preclinical Development, Aptuit (Verona) S.r.l., an Evotec Company, DD&D Research Centre, Verona, Italy
⨯
Antonio Felici,

Roles Supervision, Writing – review & editing

Affiliation In vitro Pharmacology, Microbiology Discovery, Aptuit (Verona) S.r.l., an Evotec Company, DD&D Research Centre, Verona, Italy

https://orcid.org/0000-0003-2918-5427

⨯
Livia Ferrari

Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation Translational Microbiology, Antibacterial Discovery, Aptuit (Verona) S.r.l., an Evotec Company DD&D Research Centre, Verona, Italy
⨯

Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques

Gabriella Bergamini,
Maria Elisa Perico,
Stefano Di Palma,
Daniela Sabatini,
Filippo Andreetta,
Rossella Defazio,
Antonio Felici,
Livia Ferrari

Published: December 2, 2021
https://doi.org/10.1371/journal.pone.0260627

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