Baseline mean platelet volume is a strong predictor of major and life-threatening bleedings after transcatheter aortic valve replacement

Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Adrien Carmona; Sébastien Hess; Marion Kibler; Joé Heger; Antje Reydel; Laurent Sattler; Lelia Grunebaum; Laurence Jesel; Patrick Ohlmann; Olivier Morel

doi:10.1371/journal.pone.0260439

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Open Access

Peer-reviewed

Research Article

Baseline mean platelet volume is a strong predictor of major and life-threatening bleedings after transcatheter aortic valve replacement

Antonin Trimaille,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France, INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, FMTS, Strasbourg, France

https://orcid.org/0000-0001-9279-4220

⨯
Kensuke Matsushita,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliations Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France, INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, FMTS, Strasbourg, France
⨯
Benjamin Marchandot,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France

https://orcid.org/0000-0001-7034-1466

⨯
Adrien Carmona,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France
⨯
Sébastien Hess,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France
⨯
Marion Kibler,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France
⨯
Joé Heger,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France
⨯
Antje Reydel,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France
⨯
Laurent Sattler,

Roles Data curation, Formal analysis, Investigation, Validation

Affiliation Department of Hemostasis, Hôpital de Hautepierre, Strasbourg University Hospital, Strasbourg, France

https://orcid.org/0000-0003-2702-6246

⨯
Lelia Grunebaum,

Roles Data curation, Formal analysis, Investigation, Validation

Affiliation Department of Hemostasis, Hôpital de Hautepierre, Strasbourg University Hospital, Strasbourg, France
⨯
Laurence Jesel,

Roles Data curation, Formal analysis, Investigation, Validation

Affiliations Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France, INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, FMTS, Strasbourg, France
⨯
Patrick Ohlmann,

Roles Data curation, Formal analysis, Investigation, Validation

Affiliation Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France
⨯
Olivier Morel

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: olivier.morel@chru-strasbourg.fr

Affiliations Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France, INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, FMTS, Strasbourg, France
⨯

Baseline mean platelet volume is a strong predictor of major and life-threatening bleedings after transcatheter aortic valve replacement

Antonin Trimaille,
Kensuke Matsushita,
Benjamin Marchandot,
Adrien Carmona,
Sébastien Hess,
Marion Kibler,
Joé Heger,
Antje Reydel,
Laurent Sattler,
Lelia Grunebaum

Published: November 30, 2021
https://doi.org/10.1371/journal.pone.0260439

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Hemorrhage
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Platelets
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Medical risk factors
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Anticoagulant therapy
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Platelet activation
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Aortic valve replacement
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Myocardial infarction
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