The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth

• Ryan V. Moriarty ,

  Contributed equally to this work with: Ryan V. Moriarty, Athena E. Golfinos

  Roles Formal analysis, Validation, Writing – review & editing

  Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Microbiology Doctoral Training Program, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0001-7100-1906

  ⨯
• Athena E. Golfinos ,

  Contributed equally to this work with: Ryan V. Moriarty, Athena E. Golfinos

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  ⨯
• Dane D. Gellerup,

  Roles Investigation, Methodology

  Affiliation Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America

  ⨯
• Hannah Schweigert,

  Roles Investigation, Methodology

  Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  ⨯
• Jaffna Mathiaparanam,

  Roles Investigation, Methodology

  Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  ⨯
• Alexis J. Balgeman,

  Roles Investigation

  Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  ⨯
• Andrea M. Weiler,

  Roles Investigation, Methodology

  Affiliations Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  ⨯
• Thomas C. Friedrich,

  Roles Supervision

  Affiliations Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0001-9831-6895

  ⨯
• Brandon F. Keele,

  Roles Resources, Software, Writing – review & editing

  Affiliation AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD, United States of America

  ⨯
• Miles P. Davenport,

  Roles Methodology

  Affiliation Infection Analytics Program, Kirby Institute for Infection and Immunity, UNSW Sydney, Sydney, NSW, Australia

  ⨯
• Vanessa Venturi,

  Roles Resources, Software

  Affiliation Infection Analytics Program, Kirby Institute for Infection and Immunity, UNSW Sydney, Sydney, NSW, Australia

  ⨯
• Shelby L. O’Connor

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

  * E-mail: slfeinberg@wisc.edu

  Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0003-0183-5010

  ⨯