Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer

Ami G. Sangster; Robert J. Gooding; Andrew Garven; Hamid Ghaedi; David M. Berman; Scott K. Davey

doi:10.1371/journal.pone.0259992

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Open Access

Peer-reviewed

Research Article

Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer

Ami G. Sangster,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliation Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen’s University Cancer Research Institute, Kingston, Ontario, Canada

https://orcid.org/0000-0003-1326-4278

⨯
Robert J. Gooding,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Physics, Queen’s University, Kingston, Ontario, Canada
⨯
Andrew Garven,

Roles Formal analysis

Affiliation Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen’s University Cancer Research Institute, Kingston, Ontario, Canada
⨯
Hamid Ghaedi,

Roles Formal analysis

Affiliation Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen’s University Cancer Research Institute, Kingston, Ontario, Canada
⨯
David M. Berman,

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen’s University Cancer Research Institute, Kingston, Ontario, Canada

https://orcid.org/0000-0001-5985-3698

⨯
Scott K. Davey

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: scott.davey@queensu.ca

Affiliation Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Queen’s University Cancer Research Institute, Kingston, Ontario, Canada

https://orcid.org/0000-0001-8909-8064

⨯

Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer

Ami G. Sangster,
Robert J. Gooding,
Andrew Garven,
Hamid Ghaedi,
David M. Berman,
Scott K. Davey

Published: January 24, 2022
https://doi.org/10.1371/journal.pone.0259992

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Mutation
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Bladder cancer
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Somatic mutation
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Cancers and neoplasms
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Cell cycle and cell division
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Epistasis
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Histones
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