Ketamine for critically ill patients with severe acute brain injury: Protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials

Frederik Andreas Madsen; Trine Hjorslev Andreasen; Jane Lindschou; Christian Gluud; Kirsten Møller

doi:10.1371/journal.pone.0259899

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Ketamine for critically ill patients with severe acute brain injury: Protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials

Frederik Andreas Madsen ,

Contributed equally to this work with: Frederik Andreas Madsen, Trine Hjorslev Andreasen

Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Neuroanaesthesiology, Neuroscience Centre, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark
⨯
Trine Hjorslev Andreasen ,

Contributed equally to this work with: Frederik Andreas Madsen, Trine Hjorslev Andreasen

Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: trine.hjorslev.andreasen@regionh.dk

Affiliations Department of Neurosurgery, Neuroscience Centre, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

https://orcid.org/0000-0001-5707-8712

⨯
Jane Lindschou,

Roles Methodology, Supervision

Affiliation Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark
⨯
Christian Gluud,

Roles Supervision, Writing – review & editing

Affiliations Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark, Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
⨯
Kirsten Møller

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations Department of Neuroanaesthesiology, Neuroscience Centre, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

https://orcid.org/0000-0003-3058-1072

⨯

Ketamine for critically ill patients with severe acute brain injury: Protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials

Frederik Andreas Madsen,
Trine Hjorslev Andreasen,
Jane Lindschou,
Christian Gluud,
Kirsten Møller

Published: November 15, 2021
https://doi.org/10.1371/journal.pone.0259899

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