Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches

Sara Stinca; Thomas W. Barnes; Peter Vogel; Wilfried Meyers; Johannes Schulte-Pelkum; Daniel Filchtinski; Laura Steller; Thomas Hauser; Sandro Manni; David F. Gardiner; Sharon Popik; Nathan J. Roth; Patrick Schuetz

doi:10.1371/journal.pone.0259731

Loading metrics

Open Access

Peer-reviewed

Research Article

Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches

Sara Stinca ,

Contributed equally to this work with: Sara Stinca, Thomas W. Barnes

Roles Data curation, Formal analysis, Methodology, Project administration, Visualization

Affiliation Department of Bioanalytical Sciences, Plasma Product Development, Research & Development, CSL Behring AG, Bern, Switzerland
⨯
Thomas W. Barnes ,

Contributed equally to this work with: Sara Stinca, Thomas W. Barnes

Roles Data curation, Formal analysis, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Bioanalytical Sciences, Plasma Product Development, Research & Development, CSL Behring AG, Bern, Switzerland
⨯
Peter Vogel,

Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Global Digital Core, Plasma Product Development, Research & Development, CSL Behring Innovation GmbH, Marburg, Germany
⨯
Wilfried Meyers,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Global Digital Core, Plasma Product Development, Research & Development, CSL Behring Innovation GmbH, Marburg, Germany
⨯
Johannes Schulte-Pelkum,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Assay Design, Thermo Fisher Scientific ImmunoDiagnostics Phadia GmbH, Freiburg, Germany
⨯
Daniel Filchtinski,

Roles Investigation, Methodology

Affiliation Assay Design, Thermo Fisher Scientific ImmunoDiagnostics Phadia GmbH, Freiburg, Germany

https://orcid.org/0000-0003-1875-2422

⨯
Laura Steller,

Roles Investigation, Methodology

Affiliation Assay Design, Thermo Fisher Scientific ImmunoDiagnostics Phadia GmbH, Freiburg, Germany
⨯
Thomas Hauser,

Roles Investigation, Methodology, Visualization

Affiliation Department of Bioanalytical Sciences, Plasma Product Development, Research & Development, CSL Behring AG, Bern, Switzerland
⨯
Sandro Manni,

Roles Writing – review & editing

Affiliation Department of Bioanalytical Sciences, Plasma Product Development, Research & Development, CSL Behring AG, Bern, Switzerland
⨯
David F. Gardiner,

Roles Writing – original draft

Affiliation Immunology, CSL Behring, King of Prussia, Pennsylvania, United States of America
⨯
Sharon Popik,

Roles Writing – review & editing

Affiliation Immunology, CSL Behring, King of Prussia, Pennsylvania, United States of America
⨯
Nathan J. Roth,

Roles Conceptualization, Resources, Supervision

Affiliation Department of Bioanalytical Sciences, Plasma Product Development, Research & Development, CSL Behring AG, Bern, Switzerland
⨯
Patrick Schuetz

Roles Conceptualization, Resources, Supervision

* E-mail: Patrick.Schuetz@cslbehring.com

Affiliation Department of Bioanalytical Sciences, Plasma Product Development, Research & Development, CSL Behring AG, Bern, Switzerland

https://orcid.org/0000-0002-7153-1488

⨯

Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches

Sara Stinca,
Thomas W. Barnes,
Peter Vogel,
Wilfried Meyers,
Johannes Schulte-Pelkum,
Daniel Filchtinski,
Laura Steller,
Thomas Hauser,
Sandro Manni,
David F. Gardiner

Published: November 29, 2021
https://doi.org/10.1371/journal.pone.0259731

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Vaccination and immunization
Is the Subject Area "Vaccination and immunization" applicable to this article?

Thanks for your feedback.
COVID 19
Is the Subject Area "COVID 19" applicable to this article?

Thanks for your feedback.
SARS CoV 2
Is the Subject Area "SARS CoV 2" applicable to this article?

Thanks for your feedback.
Viral vaccines
Is the Subject Area "Viral vaccines" applicable to this article?

Thanks for your feedback.
Vaccine development
Is the Subject Area "Vaccine development" applicable to this article?

Thanks for your feedback.
Mathematical models
Is the Subject Area "Mathematical models" applicable to this article?

Thanks for your feedback.
Vaccines
Is the Subject Area "Vaccines" applicable to this article?

Thanks for your feedback.