Chromosomal variants accumulate in genomes of the spontaneous aborted fetuses revealed by chromosomal microarray analysis

Sen Li; Lei-Ling Chen; Xing-Hua Wang; Hai-Jing Zhu; Xiao-Long Li; Xie Feng; Lei Guo; Xiang-Hong Ou; Jun-Yu Ma

doi:10.1371/journal.pone.0259518

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Open Access

Peer-reviewed

Research Article

Chromosomal variants accumulate in genomes of the spontaneous aborted fetuses revealed by chromosomal microarray analysis

Sen Li,

Roles Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Writing – original draft

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Lei-Ling Chen,

Roles Data curation, Formal analysis

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Xing-Hua Wang,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Hai-Jing Zhu,

Roles Data curation, Investigation

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Xiao-Long Li,

Roles Data curation, Investigation, Methodology

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Xie Feng,

Roles Project administration

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Lei Guo,

Roles Data curation, Methodology, Project administration

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China
⨯
Xiang-Hong Ou,

Roles Data curation

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China, Bioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China
⨯
Jun-Yu Ma

Roles Conceptualization, Formal analysis, Supervision, Visualization, Writing – original draft

* E-mail: majy@gd2h.org.cn

Affiliations Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, China, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China

https://orcid.org/0000-0002-3339-7863

⨯

Chromosomal variants accumulate in genomes of the spontaneous aborted fetuses revealed by chromosomal microarray analysis

Sen Li,
Lei-Ling Chen,
Xing-Hua Wang,
Hai-Jing Zhu,
Xiao-Long Li,
Xie Feng,
Lei Guo,
Xiang-Hong Ou,
Jun-Yu Ma

Published: November 2, 2021
https://doi.org/10.1371/journal.pone.0259518

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10 Jan 2022
00:55 GMT
Most Recent

Authors' names correction Posted by jma540 on 10 Jan 2022 at 00:55 GMT

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Fetuses
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Microarrays
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Aneuploidy
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Genomics
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Assisted reproductive technology
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Miscarriage
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Termination of pregnancy
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