Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer’s patients and high-pathology controls

• Hao Jiang,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America

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• Thomas J. Esparza,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America, Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, United States of America

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• Terrance T. Kummer,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America

  https://orcid.org/0000-0001-8938-8280

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• David L. Brody

  Roles Conceptualization, Supervision, Writing – original draft

  * E-mail: David.brody@usuhs.edu

  Affiliations Department of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, United States of America, Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

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