Clinical management and outcome differences between first and second waves among COVID-19 hospitalized patients: A regional prospective observational cohort

María Zuil; Iván D. Benítez; Ramón Cabo-Gambín; Carlos Manzano Senra; Anna Moncusí-Moix; Clara Gort-Paniello; David de Gonzalo-Calvo; Marta Molinero; Jose Javier Vengoechea Aragoncillo; Thais Comella; Jordi de Batlle; Gerard Torres; Antoni Torres; Ferrán Barbé; Jessica González

doi:10.1371/journal.pone.0258918

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Open Access

Peer-reviewed

Research Article

Clinical management and outcome differences between first and second waves among COVID-19 hospitalized patients: A regional prospective observational cohort

María Zuil,

Roles Conceptualization, Investigation, Writing – original draft

Affiliation Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain
⨯
Iván D. Benítez,

Roles Data curation, Investigation

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
Ramón Cabo-Gambín,

Roles Conceptualization, Data curation, Investigation

Affiliation Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain
⨯
Carlos Manzano Senra,

Roles Conceptualization, Data curation, Investigation

Affiliation Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain
⨯
Anna Moncusí-Moix,

Roles Data curation, Investigation

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
Clara Gort-Paniello,

Roles Data curation, Investigation

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
David de Gonzalo-Calvo,

Roles Investigation, Writing – review & editing

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
Marta Molinero,

Roles Investigation

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
Jose Javier Vengoechea Aragoncillo,

Roles Investigation

Affiliation Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain
⨯
Thais Comella,

Roles Data curation, Investigation

Affiliation Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain
⨯
Jordi de Batlle,

Roles Investigation, Writing – review & editing

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
Gerard Torres,

Roles Investigation, Writing – review & editing

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
⨯
Antoni Torres,

Roles Conceptualization, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliations CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain, Pulmonary Department, Hospital Clinic, Universitat de Barcelona, IDIBAPS, ICREA, Barcelona, Spain
⨯
Ferrán Barbé,

Roles Conceptualization, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain

https://orcid.org/0000-0002-4465-1951

⨯
Jessica González

Roles Conceptualization, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: jgonzalezgutierrez88@gmail.com

Affiliations Group of Translational Research in Respiratory Medicine, IRBLleida, Hospital Universitari Arnau de Vilanova and Santa Maria, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Lleida, Spain, CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain

https://orcid.org/0000-0001-5591-5062

⨯

Clinical management and outcome differences between first and second waves among COVID-19 hospitalized patients: A regional prospective observational cohort

María Zuil,
Iván D. Benítez,
Ramón Cabo-Gambín,
Carlos Manzano Senra,
Anna Moncusí-Moix,
Clara Gort-Paniello,
David de Gonzalo-Calvo,
Marta Molinero,
Jose Javier Vengoechea Aragoncillo,
Thais Comella

Published: October 28, 2021
https://doi.org/10.1371/journal.pone.0258918

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