Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease

• Sebastian Cremer,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, Cardiology, Goethe University Hospital, Frankfurt, Germany, German Center for Cardiovascular Research DZHK, Partner Site Rhine-Main, Berlin, Germany, Cardiopulmonary Institute, Goethe University Frankfurt, Frankfurt, Germany

  https://orcid.org/0000-0002-6409-9279

  ⨯
• Lisa Pilgram,

  Roles Data curation

  Affiliation Department of Internal Medicine, Hematology/Oncology, Goethe University Frankfurt, Frankfurt am Main, Germany

  ⨯
• Alexander Berkowitsch,

  Roles Data curation, Formal analysis

  Affiliation Department of Medicine, Cardiology, Goethe University Hospital, Frankfurt, Germany

  ⨯
• Melanie Stecher,

  Roles Data curation

  Affiliation Department I for Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

  https://orcid.org/0000-0002-3460-1299

  ⨯
• Siegbert Rieg,

  Roles Data curation

  Affiliation Internal Medicine II, Department of Infectious Diseases, Freiburg University Hospital, Freiburg, Germany

  ⨯
• Mariana Shumliakivska,

  Roles Data curation

  Affiliation Institute for Cardiovascular Regeneration, Goethe University Frankfurt, Frankfurt, Germany

  https://orcid.org/0000-0001-6696-9103

  ⨯
• Denisa Bojkova,

  Roles Data curation

  Affiliation Institute of Medical Virology, University of Frankfurt, Frankfurt, Germany

  ⨯
• Julian Uwe Gabriel Wagner,

  Roles Data curation

  Affiliation Institute for Cardiovascular Regeneration, Goethe University Frankfurt, Frankfurt, Germany

  ⨯
• Galip Servet Aslan,

  Roles Data curation

  Affiliation Institute for Cardiovascular Regeneration, Goethe University Frankfurt, Frankfurt, Germany

  ⨯
• Christoph Spinner,

  Roles Data curation

  Affiliation Department of Internal Medicine II, Technical University of Munich, Hospital rechts der Isar, Munich, Germany

  https://orcid.org/0000-0002-3875-5367

  ⨯
• Guillermo Luxán,

  Roles Data curation

  Affiliations German Center for Cardiovascular Research DZHK, Partner Site Rhine-Main, Berlin, Germany, Institute for Cardiovascular Regeneration, Goethe University Frankfurt, Frankfurt, Germany

  https://orcid.org/0000-0001-8350-8659

  ⨯
• Frank Hanses,

  Roles Data curation

  Affiliation University Hospital Regensburg, Regensburg, Germany

  ⨯
• Sebastian Dolff,

  Roles Data curation

  Affiliation Department of Infectious Diseases, University Hospital Essen, Essen, Germany

  ⨯
• Christiane Piepel,

  Roles Data curation

  Affiliation Department of Internal Medicine I, Hospital Bremen-Mitte, Bremen, Germany

  ⨯
• Clemens Ruppert,

  Roles Data curation

  Affiliation Department of Internal Medicine II, Giessen University, Giessen, Germany

  ⨯
• Andreas Guenther,

  Roles Data curation

  Affiliation Department of Internal Medicine II, Giessen University, Giessen, Germany

  ⨯
• Maria Madeleine Rüthrich,

  Roles Data curation

  Affiliation Department of Internal Medicine II, Jena University, Jena, Germany

  ⨯
• Jörg Janne Vehreschild,

  Roles Data curation

  Affiliation Department I for Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

  ⨯
• Kai Wille,

  Roles Data curation

  Affiliation University Clinic for Hematology, Oncology, Hemostaseology and Palliative Care, University of Bochum, Minden, Germany

  ⨯
• Martina Haselberger,

  Roles Data curation

  Affiliation Department of Internal Medicine I, Hospital Passau, Passau, Germany

  https://orcid.org/0000-0001-6166-4255

  ⨯
• Hanno Heuzeroth,

  Roles Data curation

  Affiliation Department of Emergency and Intensive Care Medicine, Klinikum Ernst von Bergmann, Potsdam, Germany

  ⨯
• Arne Hansen,

  Roles Data curation

  Affiliation Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

  ⨯
• Thomas Eschenhagen,

  Roles Data curation

  Affiliation Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

  ⨯
• Jindrich Cinatl,

  Roles Data curation

  Affiliation Institute of Medical Virology, University of Frankfurt, Frankfurt, Germany

  ⨯
• Sandra Ciesek,

  Roles Data curation

  Affiliation Institute of Medical Virology, University of Frankfurt, Frankfurt, Germany

  ⨯
• Stefanie Dimmeler,

  Roles Conceptualization, Data curation

  Affiliations German Center for Cardiovascular Research DZHK, Partner Site Rhine-Main, Berlin, Germany, Cardiopulmonary Institute, Goethe University Frankfurt, Frankfurt, Germany, Institute for Cardiovascular Regeneration, Goethe University Frankfurt, Frankfurt, Germany

  ⨯
• Stefan Borgmann ,

  Roles Data curation

  ¶‡ SB and AZ shared last authorship on this work.

  Affiliation Department of Infectious Diseases and Infection Control, Ingolstadt Hospital, Ingolstadt, Germany

  ⨯
• Andreas Zeiher ,

  Roles Conceptualization, Supervision

  * E-mail: zeiher@em.uni-frankfurt.de

  ¶‡ SB and AZ shared last authorship on this work.

  Affiliations Department of Medicine, Cardiology, Goethe University Hospital, Frankfurt, Germany, German Center for Cardiovascular Research DZHK, Partner Site Rhine-Main, Berlin, Germany, Cardiopulmonary Institute, Goethe University Frankfurt, Frankfurt, Germany

  ⨯
•  [ ... ],
• on behalf of the LEOSS study group

  ¶Membership of the LEOSS study group is listed in the Acknowledgments.

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