Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3

• Vijay Kumar,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Samantha L. Viviani,

  Roles Data curation, Investigation

  Affiliation Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Jeeda Ismail,

  Roles Investigation

  Affiliation Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Shreya Agarwal,

  Roles Investigation

  Affiliation Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Robert A. Bonomo,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America, Louis Stokes Cleveland Veteran’s Affairs Medical Center Research Service, Cleveland, Ohio, United States of America, Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America, VA Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Case Western Reserve University, Cleveland, Ohio, United States of America

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• Focco van den Akker

  Roles Conceptualization, Formal analysis, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: focco.vandenakker@case.edu

  Affiliation Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America

  https://orcid.org/0000-0001-9210-3565

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