Analysis of acute lymphoblastic leukemia drug sensitivity by changes in impedance via stromal cell adherence

Annie Luong; Fabio Cerignoli; Yama Abassi; Nora Heisterkamp; Hisham Abdel-Azim

doi:10.1371/journal.pone.0258140

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Peer-reviewed

Research Article

Analysis of acute lymphoblastic leukemia drug sensitivity by changes in impedance via stromal cell adherence

Annie Luong ,

Contributed equally to this work with: Annie Luong, Fabio Cerignoli, Nora Heisterkamp, Hisham Abdel-Azim

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Division of Hematology, Oncology and Bone Marrow Transplantation, Children’s Hospital Los Angeles, Los Angeles, CA, United States of America
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Fabio Cerignoli ,

Contributed equally to this work with: Annie Luong, Fabio Cerignoli, Nora Heisterkamp, Hisham Abdel-Azim

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Agilent Technologies, Inc., Santa Clara, CA, United States of America
⨯
Yama Abassi,

Roles Formal analysis, Methodology, Resources

Affiliation Agilent Technologies, Inc., Santa Clara, CA, United States of America
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Nora Heisterkamp ,

Contributed equally to this work with: Annie Luong, Fabio Cerignoli, Nora Heisterkamp, Hisham Abdel-Azim

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Systems Biology, Beckman Research Institute City of Hope, Monrovia, CA, United States of America
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Hisham Abdel-Azim

Contributed equally to this work with: Annie Luong, Fabio Cerignoli, Nora Heisterkamp, Hisham Abdel-Azim

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: habdelazim@chla.usc.edu

Affiliations Division of Hematology, Oncology and Bone Marrow Transplantation, Children’s Hospital Los Angeles, Los Angeles, CA, United States of America, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America

https://orcid.org/0000-0003-0880-8701

⨯

Analysis of acute lymphoblastic leukemia drug sensitivity by changes in impedance via stromal cell adherence

Annie Luong,
Fabio Cerignoli,
Yama Abassi,
Nora Heisterkamp,
Hisham Abdel-Azim

Published: September 30, 2021
https://doi.org/10.1371/journal.pone.0258140

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Stromal cells
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Drug therapy
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Cancer treatment
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Cell proliferation
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