Bergamottin a CYP3A inhibitor found in grapefruit juice inhibits prostate cancer cell growth by downregulating androgen receptor signaling and promoting G0/G1 cell cycle block and apoptosis

• Opalina Vetrichelvan,

  Roles Data curation, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

  Affiliation Department of Biomedical Sciences, College of Medicine, Roseman University of Health Sciences, Las Vegas, Nevada, United States of America

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• Priyatham Gorjala,

  Roles Data curation, Investigation, Methodology, Software, Visualization

  Affiliation Department of Biomedical Sciences, College of Medicine, Roseman University of Health Sciences, Las Vegas, Nevada, United States of America

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• Oscar Goodman Jr.,

  Roles Conceptualization, Investigation, Visualization, Writing – review & editing

  Affiliations Department of Biomedical Sciences, College of Medicine, Roseman University of Health Sciences, Las Vegas, Nevada, United States of America, Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States of America

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• Ranjana Mitra

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rmitra@roseman.edu

  Affiliation Department of Biomedical Sciences, College of Medicine, Roseman University of Health Sciences, Las Vegas, Nevada, United States of America

  https://orcid.org/0000-0001-9421-3610

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