Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway

• Swechha M. Pokharel ,

  Contributed equally to this work with: Swechha M. Pokharel, Kim Chiok

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

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• Kim Chiok ,

  Contributed equally to this work with: Swechha M. Pokharel, Kim Chiok

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

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• Niraj K. Shil,

  Roles Conceptualization, Formal analysis, Visualization

  Current address: Symbio Labs, Brooklyn, Victoria, Australia

  Affiliation Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

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• Indira Mohanty,

  Roles Formal analysis, Methodology

  Affiliation Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

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• Santanu Bose

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: santanu.bose@wsu.edu

  Affiliation Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America

  https://orcid.org/0000-0002-8137-7568

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