LTA4H rs2660845 association with montelukast response in early and late-onset asthma

• Cyrielle Maroteau ,

  Roles Data curation, Formal analysis, Validation, Writing – original draft, Writing – review & editing

  * E-mail: c.maroteau@dundee.ac.uk

  Affiliations Centre for Genomics Research, Discovery Science, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom, Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

  https://orcid.org/0000-0001-7816-5508

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• Antonio Espuela-Ortiz,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain

  https://orcid.org/0000-0003-0572-9549

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• Esther Herrera-Luis,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain

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• Sundararajan Srinivasan,

  Roles Resources, Writing – review & editing

  Affiliation Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

  ⨯
• Fiona Carr,

  Roles Resources, Writing – review & editing

  Affiliation Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

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• Roger Tavendale,

  Roles Resources, Writing – review & editing

  Affiliation Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

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• Karen Wilson,

  Roles Resources, Writing – review & editing

  Affiliation Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

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• Natalia Hernandez-Pacheco,

  Roles Project administration, Writing – review & editing

  Affiliations Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain, Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, San Cristobal de La Laguna, Spain

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• James D. Chalmers,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom

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• Steve Turner,

  Roles Conceptualization, Funding acquisition, Validation, Writing – review & editing

  Affiliation Child Health, University of Aberdeen, Aberdeen, United Kingdom

  https://orcid.org/0000-0001-8393-5060

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• Somnath Mukhopadhyay,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Academic Department of Pediatrics, Brighton and Sussex Medical School, Royal Alexandra Children’s Hospital, Brighton, United Kingdom

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• Anke-Hilse Maitland-van der Zee,

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Validation, Writing – review & editing

  Affiliations Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands, Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands, Department of Pediatric Respiratory Medicine and Allergy, Emma’s Children Hospital, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands

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• Esteban G. Burchard,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Writing – review & editing

  Affiliations Department of Medicine, University of California San Francisco, San Francisco, California, United States of America, Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America

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• Maria Pino-Yanes,

  Roles Data curation, Funding acquisition, Resources, Writing – review & editing

  Affiliations Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Comunidad de Madrid, Spain, Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain

  https://orcid.org/0000-0003-0332-437X

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• Simon Young,

  Roles Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliations BioPharmaceutical Precision Medicine, Oncology R&D, AstraZeneca, Cambridge, United Kingdom, Research & Development Centre, Sysmex, Cambridge, United Kingdom

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• Glenda Lassi,

  Roles Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  Affiliation Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom

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• Adam Platt,

  Roles Conceptualization, Investigation, Project administration, Supervision, Validation, Writing – review & editing

  Affiliation Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom

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• Colin N. A. Palmer,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

  Affiliation Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

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•  [ ... ],
• on behalf of the PiCA Consortium

  ¶Membership of the Pharmacogenetics in Childhood Asthma Consortium is listed in the Acknowledgments.

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