Genomic mutation profile in progressive chronic lymphocytic leukemia patients prior to first-line chemoimmunotherapy with FCR and rituximab maintenance (REM)

• Julia González-Rincón,

  Roles Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft

  Affiliations Lymphoma Research Group, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDPHISA), Madrid, Spain, Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

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• José A. Garcia-Vela,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Hematology Department, Hospital Universitario de Getafe, Madrid, Spain

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• Sagrario Gómez,

  Roles Methodology, Validation, Visualization

  Affiliation Lymphoma Research Group, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDPHISA), Madrid, Spain

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• Belén Fernández-Cuevas,

  Roles Methodology, Visualization

  Affiliation Hematology Department, Hospital Universitario Puerta de Hierro-Majadahonda and Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Madrid, Spain

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• Sara Nova-Gurumeta,

  Roles Methodology, Visualization

  Affiliation Hematology Department, Hospital Universitario Puerta de Hierro-Majadahonda and Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Madrid, Spain

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• Nuria Pérez-Sanz,

  Roles Methodology, Visualization

  Affiliation Hematology Department, Hospital Universitario Puerta de Hierro-Majadahonda and Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Madrid, Spain

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• Miguel Alcoceba,

  Roles Formal analysis, Resources, Visualization

  Affiliations Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain, Hematology, Hospital Universitario de Salamanca, Salamanca, Spain

  https://orcid.org/0000-0002-3819-4846

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• Marcos González,

  Roles Funding acquisition, Resources, Visualization

  Affiliations Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain, Hematology, Hospital Universitario de Salamanca, Salamanca, Spain

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• Eduardo Anguita,

  Roles Resources, Validation

  Affiliation Hematology, Hospital Clínico San Carlos, IdISSC, UCM, Madrid, Spain

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• Javier López-Jiménez,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Ramon y Cajal, Madrid, Spain

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• Eva González-Barca,

  Roles Resources, Visualization

  Affiliation Hematology, Institut Català d’Oncologia, IDIBELL, L’Hospitalet de LLobregat, Spain

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• Lucrecia Yáñez,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Universitario Marqués de Valdecilla, Santander, Spain

  https://orcid.org/0000-0001-9925-3048

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• Ernesto Pérez-Persona,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Txagorritxu, Vitoria, Spain

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• Javier de la Serna,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Doce de Octubre, Madrid, Spain

  https://orcid.org/0000-0003-3904-1101

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• Miguel Fernández-Zarzoso,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Universitario Dr Peset, Valencia, Spain

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• Guillermo Deben,

  Roles Resources, Visualization

  Affiliation Hematology, CHU Juan Canalejo, A Coruña, Spain

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• Francisco J. Peñalver,

  Roles Resources, Visualization

  Affiliation Hematology, Fundación Hospital de Alcorcón, Madrid, Spain

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• María C. Fernández,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Universitario Puerta del Mar, Cadiz, Spain

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• Jaime Pérez de Oteyza,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Madrid Norte Sanchinarro, Madrid, Spain

  https://orcid.org/0000-0002-8338-2037

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• M. Ángeles Andreu,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital General de Móstoles, Madrid, Spain

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• M. Ángeles Ruíz-Guinaldo,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Francesc Borja, Valencia, Spain

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• Raquel Paz-Arias,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Universitario La Paz, Madrid, Spain

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• M. Dolores García-Malo,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Morales Meseguer, Murcia, Spain

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• Valle Recasens,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Miguel Servet, Zaragoza, Spain

  https://orcid.org/0000-0001-5129-8597

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• Rosa Collado,

  Roles Resources, Visualization

  Affiliation Citogenetics and molecular biology laboratory, Consorcio Hospital General Universitario, Valencia, Spain

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• Raúl Córdoba,

  Roles Resources, Visualization

  Affiliation Hematology, Hospital Fundación Jiménez Díaz, Madrid, Spain

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• Belén Navarro-Matilla,

  Roles Resources, Validation

  Affiliation Hematology Department, Hospital Universitario Puerta de Hierro-Majadahonda and Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Madrid, Spain

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• Margarita Sánchez-Beato ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: msbeato@idiphim.org (MSB); jagarciam@aehh.org (JAGM)

  ¶‡ MSB and JAGM contributed equally to this work as co-first authors.

  Affiliations Lymphoma Research Group, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDPHISA), Madrid, Spain, Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

  https://orcid.org/0000-0002-0058-7599

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•  [ ... ],
• José A. García-Marco

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: msbeato@idiphim.org (MSB); jagarciam@aehh.org (JAGM)

  ¶‡ MSB and JAGM contributed equally to this work as co-first authors.

  Affiliation Hematology Department, Hospital Universitario Puerta de Hierro-Majadahonda and Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Madrid, Spain

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