Intrapleural use of urokinase and DNase in pleural infections managed with repeated thoracentesis: A comparative cohort study

• David Luque Paz ,

  Roles Formal analysis, Investigation, Software, Writing – original draft

  * E-mail: david.luque.paz@chu-rennes.fr

  Affiliations Department of Respiratory Diseases, Rennes University Hospital, Rennes, France, Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France, University of Rennes, Inserm, BRM (Bacterial Regulatory RNAs and Medicine), UMR 1230, Rennes, France

  https://orcid.org/0000-0002-9197-7305

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• Betsega Bayeh,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Pneumology and Respiratory Functional Exploration, University Hospital of Tours, Tours, France

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• Pierre Chauvin,

  Roles Writing – review & editing

  Affiliation Department of Respiratory Diseases, Rennes University Hospital, Rennes, France

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• Florence Poizeau,

  Roles Formal analysis, Software

  Affiliations EA 7449 (Pharmacoepidemiology and Health Services Research) REPERES, Univ Rennes, CHU Rennes, Rennes, France, PEPS Research Consortium (Pharmacoepidemiology for Health Product Safety), Rennes, France, Department of Dermatology, CHU Rennes, Rennes, France

  https://orcid.org/0000-0002-0754-361X

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• Mathieu Lederlin,

  Roles Writing – review & editing

  Affiliation Department of Radiology, Pontchaillou University Hospital, Rennes, France

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• Mallorie Kerjouan,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Respiratory Diseases, Rennes University Hospital, Rennes, France

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• Charles Lefevre,

  Roles Writing – review & editing

  Affiliation Biochemistry Laboratory, Pontchaillou Hospital CHU Rennes, Rennes, France

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• Bertrand de Latour,

  Roles Writing – review & editing

  Affiliation Department of Thoracic and Cardiovascular Surgery, Rennes University Hospital, Rennes, France

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• Julien Letheulle,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Laval Center Hospital, Laval, France

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• Pierre Tattevin,

  Roles Conceptualization, Supervision, Validation, Writing – review & editing

  Affiliations Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France, University of Rennes, Inserm, BRM (Bacterial Regulatory RNAs and Medicine), UMR 1230, Rennes, France

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• Stéphane Jouneau

  Roles Conceptualization, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Respiratory Diseases, Rennes University Hospital, Rennes, France, University of Rennes, CHU Rennes, Inserm, EHESP, IRSET (Institut de recherche en santé, environnement et travail)—UMR_S 1085, Rennes, France

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