Beneficial effects of a plant-fish oil, slow carbohydrate diet on cardio-metabolic health exceed the correcting effects of metformin-pioglitazone in diabetic pigs fed a fast-food diet

• Sietse J. Koopmans ,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sietsejan.koopmans@wur.nl

  Affiliation Wageningen Livestock Research, Wageningen University & Research, Wageningen, The Netherlands

  https://orcid.org/0000-0001-8238-4770

  ⨯
• Heleen M. M. van Beusekom,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Experimental Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands

  https://orcid.org/0000-0002-2930-1152

  ⨯
• F. Josef van der Staay,

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Farm Animal Health, Veterinary Faculty, Utrecht University, Utrecht, The Netherlands

  ⨯
• Gisabeth Binnendijk,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Wageningen Livestock Research, Wageningen University & Research, Wageningen, The Netherlands

  ⨯
• Marcel Hulst,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Wageningen Livestock Research, Wageningen University & Research, Wageningen, The Netherlands, Wageningen Bioveterinary Research, Lelystad, The Netherlands

  ⨯
• Zlaw Mroz,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Animal Science and Bioeconomy, University of Life Sciences, Lublin, Poland

  ⨯
• Mariette T. Ackermans,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Endocrine Laboratory, Clinical Chemistry, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands

  ⨯
• Lambertus Benthem

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Inorbit Therapeutics AB, Mölndal, Gothenburg, Sweden

  ⨯