Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis

• Xun Liu,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft

  Affiliation Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

  https://orcid.org/0000-0002-2110-5018

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• Kiyoshi Yamaguchi,

  Roles Formal analysis

  Affiliation Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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• Kiyoko Takane,

  Roles Formal analysis

  Affiliation Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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• Chi Zhu,

  Roles Methodology

  Affiliation Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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• Makoto Hirata,

  Roles Resources

  Affiliations Laboratory of Genome Technology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan, Department of Genetic Medicine and Services, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

  https://orcid.org/0000-0002-9994-9958

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• Yoko Hikiba,

  Roles Resources

  Affiliation Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa Prefecture, Japan

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• Shin Maeda,

  Roles Resources

  Affiliation Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa Prefecture, Japan

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• Yoichi Furukawa,

  Roles Project administration, Supervision

  Affiliation Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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• Tsuneo Ikenoue

  Roles Conceptualization, Project administration, Supervision, Writing – original draft

  * E-mail: ikenoue@g.ecc.u-tokyo.ac.jp

  Affiliation Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

  https://orcid.org/0000-0001-8264-2573

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