Safety verification for polysorbate 20, pharmaceutical excipient for intramuscular administration, in Sprague-Dawley rats and New Zealand White rabbits

• Junhyung Kim ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

  Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

  https://orcid.org/0000-0002-6617-5837

  ⨯
• Seongsung Kwak ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

  Affiliations Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea, Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea

  https://orcid.org/0000-0001-7867-5057

  ⨯
• Mi-Sun Park,

  Roles Data curation, Investigation, Methodology, Project administration, Validation, Writing – review & editing

  Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

  ⨯
• Chang-Hoon Rhee,

  Roles Data curation, Investigation, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Osong R&D Center, Medytox Inc., Cheongju-si, Chungcheongbuk-do, Korea

  ⨯
• Gi-Hyeok Yang,

  Roles Data curation, Investigation, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

  ⨯
• Jangmi Lee,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea

  ⨯
• Woo-Chan Son ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: whkang@medytox.com (WhK); wcson32@hanmail.net (WCS)

  ¶‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

  Affiliation Department of Pathology, Asan Medical Center, Songpa-gu, Seoul, Korea

  ⨯
• Won-ho Kang

  Roles Conceptualization, Project administration, Supervision, Writing – review & editing

  * E-mail: whkang@medytox.com (WhK); wcson32@hanmail.net (WCS)

  ¶‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

  Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

  ⨯