Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Loading metrics

Open Access

Peer-reviewed

Research Article

Activation of the alpha 7 nicotinic acetylcholine receptor mitigates osteoarthritis progression by inhibiting NF-κB/NLRP3 inflammasome activation and enhancing autophagy

Xianjie Zhu ,

Contributed equally to this work with: Xianjie Zhu, Shiyou Dai, Baohua Xia

Roles Writing – original draft

Affiliation Department of Orthopedics, Qingdao Municipal Hospital, Qingdao, Shandong, China
⨯
Shiyou Dai ,

Contributed equally to this work with: Xianjie Zhu, Shiyou Dai, Baohua Xia

Roles Writing – review & editing

Affiliation Department of Orthopedics, Qingdao Municipal Hospital, Qingdao, Shandong, China
⨯
Baohua Xia ,

Contributed equally to this work with: Xianjie Zhu, Shiyou Dai, Baohua Xia

Roles Writing – original draft

Affiliation Department of Clinical Skills Training Center, Qingdao Municipal Hospital, Qingdao, Shandong, China
⨯
Jianbao Gong,

Roles Writing – review & editing

Affiliation Department of Orthopedics, Qingdao Municipal Hospital, Qingdao, Shandong, China
⨯
Bingzheng Ma

Roles Formal analysis, Investigation

* E-mail: 1018967905@qq.com

Affiliation Department of Orthopedics, Qingdao Municipal Hospital, Qingdao, Shandong, China

https://orcid.org/0000-0002-5194-4736

⨯

Activation of the alpha 7 nicotinic acetylcholine receptor mitigates osteoarthritis progression by inhibiting NF-κB/NLRP3 inflammasome activation and enhancing autophagy

Xianjie Zhu,
Shiyou Dai,
Baohua Xia,
Jianbao Gong,
Bingzheng Ma

x

Published: December 23, 2021
https://doi.org/10.1371/journal.pone.0256507

Reader Comments (0)

Post a new comment on this article

Print

Advertisement

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Chondrocytes
Is the Subject Area "Chondrocytes" applicable to this article?

Thanks for your feedback.
Osteoarthritis
Is the Subject Area "Osteoarthritis" applicable to this article?

Thanks for your feedback.
Autophagic cell death
Is the Subject Area "Autophagic cell death" applicable to this article?

Thanks for your feedback.
Inflammasomes
Is the Subject Area "Inflammasomes" applicable to this article?

Thanks for your feedback.
Cartilage
Is the Subject Area "Cartilage" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.