Radiomics machine learning study with a small sample size: Single random training-test set split may lead to unreliable results

• Chansik An ,

  Contributed equally to this work with: Chansik An, Yae Won Park

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Radiology, National Health Insurance Service Ilsan Hospital, Goyang, Korea, Research Institute, National Health Insurance Service Ilsan Hospital, Goyang, Korea

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• Yae Won Park ,

  Contributed equally to this work with: Chansik An, Yae Won Park

  Roles Investigation, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea

  https://orcid.org/0000-0001-8907-5401

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• Sung Soo Ahn ,

  Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sungsoo@yuhs.ac

  Affiliation Department of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea

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• Kyunghwa Han,

  Roles Formal analysis, Methodology, Software, Supervision, Writing – review & editing

  Affiliation Department of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea

  https://orcid.org/0000-0002-5687-7237

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• Hwiyoung Kim,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea

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• Seung-Koo Lee

  Roles Supervision

  Affiliation Department of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea

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