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The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif
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Petra Lukacik,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire, United Kingdom, Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom
⨯ - C. David Owen,
- Gemma Harris,
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Jani Reddy Bolla,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Chemistry, University of Oxford, Oxford, United Kingdom
⨯ - Sarah Picaud,
- Irfan Alibay,
- Joanne E. Nettleship,
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Louise E. Bird,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliations Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯ -
Raymond J. Owens,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliations Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯ -
Philip C. Biggin,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom
⨯ - Panagis Filippakopoulos,
- Carol V. Robinson,
- Martin A. Walsh
https://orcid.org/0000-0002-3179-7273
The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif
- Petra Lukacik,
- C. David Owen,
- Gemma Harris,
- Jani Reddy Bolla,
- Sarah Picaud,
- Irfan Alibay,
- Joanne E. Nettleship,
- Louise E. Bird,
- Raymond J. Owens,
- Philip C. Biggin
- Published: October 15, 2021
- https://doi.org/10.1371/journal.pone.0256070