Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain

Shaojing Ye; Fei Ma; Dlovan F. D. Mahmood; Katherine L. Meyer-Siegler; Raymond E. Menard; David E. Hunt; Lin Leng; Richard Bucala; Pedro L. Vera

doi:10.1371/journal.pone.0255975

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Open Access

Peer-reviewed

Research Article

Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain

Shaojing Ye ,

Contributed equally to this work with: Shaojing Ye, Fei Ma

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Research & Development, Lexington VA Health Care System, Lexington, KY, United States of America
⨯
Fei Ma ,

Contributed equally to this work with: Shaojing Ye, Fei Ma

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Research & Development, Lexington VA Health Care System, Lexington, KY, United States of America
⨯
Dlovan F. D. Mahmood,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Research & Development, Lexington VA Health Care System, Lexington, KY, United States of America
⨯
Katherine L. Meyer-Siegler,

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Natural Sciences, St Petersburg College, St Petersburg, FL, United States of America
⨯
Raymond E. Menard,

Roles Investigation, Writing – review & editing

Affiliation Department of Natural Sciences, St Petersburg College, St Petersburg, FL, United States of America
⨯
David E. Hunt,

Roles Investigation, Writing – review & editing

Affiliation Research & Development, Lexington VA Health Care System, Lexington, KY, United States of America
⨯
Lin Leng,

Roles Resources, Writing – review & editing

Affiliation Department of Internal Medicine, Yale University, New Haven, CT, United States of America
⨯
Richard Bucala,

Roles Funding acquisition, Resources, Writing – original draft, Writing – review & editing

Affiliation Department of Internal Medicine, Yale University, New Haven, CT, United States of America
⨯
Pedro L. Vera

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: Pedro.Vera@va.gov

Affiliations Research & Development, Lexington VA Health Care System, Lexington, KY, United States of America, Department of Physiology, University of Kentucky, Lexington, KY, United States of America

https://orcid.org/0000-0003-2785-7218

⨯

Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain

Shaojing Ye,
Fei Ma,
Dlovan F. D. Mahmood,
Katherine L. Meyer-Siegler,
Raymond E. Menard,
David E. Hunt,
Lin Leng,
Richard Bucala,
Pedro L. Vera

Published: August 23, 2021
https://doi.org/10.1371/journal.pone.0255975

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