Risk of aortic aneurysm and dissection following exposure to fluoroquinolones, common antibiotics, and febrile illness using a self-controlled case series study design: Retrospective analyses of three large healthcare databases in the US

Ajit A. Londhe; Chantal E. Holy; James Weaver; Sergio Fonseca; Angelina Villasis; Daniel Fife

doi:10.1371/journal.pone.0255887

Loading metrics

Open Access

Peer-reviewed

Research Article

Risk of aortic aneurysm and dissection following exposure to fluoroquinolones, common antibiotics, and febrile illness using a self-controlled case series study design: Retrospective analyses of three large healthcare databases in the US

Ajit A. Londhe,

Roles Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Current address: Amgen, Thousand Oaks, CA, United States of America

Affiliation Janssen Pharmaceutical Research and Development, LLC, Titusville, NJ, United States of America
⨯
Chantal E. Holy ,

Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: choly1@its.jnj.com

Affiliation Johnson & Johnson, New Brunswick, NJ, United States of America

https://orcid.org/0000-0002-5901-1156

⨯
James Weaver,

Roles Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Janssen Pharmaceutical Research and Development, LLC, Titusville, NJ, United States of America

https://orcid.org/0000-0003-0755-5191

⨯
Sergio Fonseca,

Roles Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliation Janssen Pharmaceutical Research and Development, LLC, Titusville, NJ, United States of America
⨯
Angelina Villasis,

Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

Affiliation Janssen Pharmaceutical Research and Development, LLC, Titusville, NJ, United States of America
⨯
Daniel Fife

Roles Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Janssen Pharmaceutical Research and Development, LLC, Titusville, NJ, United States of America
⨯

Risk of aortic aneurysm and dissection following exposure to fluoroquinolones, common antibiotics, and febrile illness using a self-controlled case series study design: Retrospective analyses of three large healthcare databases in the US

Ajit A. Londhe,
Chantal E. Holy,
James Weaver,
Sergio Fonseca,
Angelina Villasis,
Daniel Fife

Published: August 16, 2021
https://doi.org/10.1371/journal.pone.0255887

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Antibiotics
Is the Subject Area "Antibiotics" applicable to this article?

Thanks for your feedback.
Inpatients
Is the Subject Area "Inpatients" applicable to this article?

Thanks for your feedback.
Tendons
Is the Subject Area "Tendons" applicable to this article?

Thanks for your feedback.
Retinal detachment
Is the Subject Area "Retinal detachment" applicable to this article?

Thanks for your feedback.
Adverse events
Is the Subject Area "Adverse events" applicable to this article?

Thanks for your feedback.
Aneurysms
Is the Subject Area "Aneurysms" applicable to this article?

Thanks for your feedback.
Surgical and invasive medical procedures
Is the Subject Area "Surgical and invasive medical procedures" applicable to this article?

Thanks for your feedback.